Individual grip strength provides a functional window into somatosensory processes and their effects on motor behaviour in young and healthy, impaired, or ageing individuals. Variations in grip strength during hand–tool interaction may therefore be exploited in a variety of experimental tasks to study effects of a pathology or ageing-related changes on sensory, motor, or cognitive ability. However, many different factors may influence individual grip strength systematically in a given task context without being explicitly identified and controlled for. Grip strength may vary as a function of the location of the measurement device (sensor) on the fingers/hand, the shape, weight, and size of object(s) being gripped, the type of grip investigated (static versus dynamic grip), and the hand (dominant versus non-dominant) used for gripping. This study tests for factors such as sight, sound, and interactions with/between factors in a complex task context. A wearable biosensor system, designed for measuring grip strength variations in operators gripping cylindrical objects bi-manually, was used. Grip force signals were recorded from all sensors of the wearable (glove) system, including three directly task-relevant sensors for bi-manually gripping cylindrical objects with the dominant and non-dominant hands. Five young male participants were tested for the effects of sound, movement, and sight on grip strength. The participants had to pick up two cylindrical objects of identical size and weight, then hold them still (static grip) or move them upwards and downwards (dynamic grip) for ten seconds while listening to soft or hard music, with their eyes open or blindfolded. Significant effects of sensor location, hand, movement, sight, and sound on bi-manual grip strength were found. Stronger grip force signals were produced by task-relevant sensors in the dominant hand when moving the cylindrical handles (dynamic grip) in comparison with the static grip condition, depending, as expected, on whether grip signals were measured from the dominant or the non-dominant hand. Significantly stronger grip strength was produced blindfolded (sight condition), and grips were significantly stronger with exposure to harder music (sound factor). It is concluded that grip strength is significantly influenced by sensory factors, and interactions between these and other factors, pointing towards the need for identifying and systematically controlling such potential sources of variation in complex study task contexts.