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Journal articles
Antibody kinetics in infants exposed to Chikungunya virus infection during pregnancy reveals absence of congenital infection
Abstract : To search for serological evidence of congenital infection in apparently healthy neonates born to women infected with the Chikungunya virus (CHIKV) during pregnancy, monitoring for CHIKV-specific antibodies was performed within the CHIMERE cohort study (Reunion island, 2006-2008). CHIKV-specific antibody kinetics showed no evidence of asymptomatic congenital infection as neonates were tested negative for CHIKV-specific IgM antibodies at birth and 368 infants with CHIKV-specific IgG antibodies seroreversed completely (mean seroreversion time: 7.7 months). Seroreversion time of transplacental CHIKV IgG antibodies was inversely correlated with the stage of pregnancy at which exposure took place and end-term small for gestational infants seroreversed earlier.
https://hal.univ-reunion.fr/hal-01274572
Contributor : Réunion Univ Connect in order to contact the contributor
Submitted on : Tuesday, February 16, 2016 - 8:41:07 AM
Last modification on : Wednesday, October 20, 2021 - 3:22:23 AM
Contributor : Réunion Univ Connect in order to contact the contributor
Submitted on : Tuesday, February 16, 2016 - 8:41:07 AM
Last modification on : Wednesday, October 20, 2021 - 3:22:23 AM
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