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, APA) soit reconnue efficace en tant que soin de support en oncologie, les modalités d'une intervention efficiente en hématologie restent à définir 2 . Cette étude de faisabilité à 6 semaines s'inscrit dans la perspective d'un essai contrôlé randomisé incluant un programme d'APA de 12 semaines qui débutera en octobre 2017 au CHU de la Réunion, chez des patients en rémission d'une hémopathie maligne. Nous rapportons ici la faisabilité, Contexte et objectifs L'altération de la qualité de vie perdure jusqu'à trois ans après une allogreffe 1 . Bien que l'Activité Physique Adaptée

, A l'inclusion et à 6 semaines, la passation des questionnaires de qualité de vie (QLQ-C30), d'anxiété et de dépression (HADS) et de fatigue (MFI-20la fatigue générale -1±1, MFI-20), du fonctionnement +7.3±10, des symptômes -7.3±10 (QLQ-C30) et de l'anxiété -1.9±4.1 (HADS), bien que ces résultats ne soient pas significatifs, vol.9

, En conclusion, nos résultats confirment l'intérêt d'un programme d'APA et l'adhésion des patients, même tardivement après une allogreffe, et sont prometteurs pour l'élaboration de l'étude randomisée débutant prochainement avec une intervention de 12 semaines en post-traitement plus précoce

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L. Variabilité-de-la-fréquence-cardiaque, Un niveau élevé de VFC indique une bonne santé, un niveau faible favorise le développement de pathologies cardiovasculaires. Aussi, les cancers et leurs traitements impactent le SNA et la VFC

, Nous évaluons la faisabilité d'un entraînement à la Cohérence Cardiaque (CC) par biofeedback de 12 semaines chez des patients adultes en rémission d'une hémopathie maligne et ses effets sur la VFC

, Cette étude s'appuie sur un essai contrôlé randomisé évaluant un programme combinant Activité Physique Adaptée (APA) et CC

, Seize patients randomisés en 2 groupes : CC + APA (n=8) ou APA (n=8), suivaient 10 séances de CC et/ou 24 séances d'APA. La CC comprenait des exercices de respiration avec biofeedback et des exercices quotidiens. L'APA

S. Le, Standard Deviation of Normal to Normal R-R interval) et l'analyse fréquentielle de la VFC sont calculés à partir d'un enregistrement de 5 min avec un capteur de pouls. Les mesures ont été comparées entre les groupes avant (T1), après 6 semaines (T2)

, 6±0.7) pour la CC et de 87.6% (21±3.2) pour l'APA, 1 perdu de vue. Nous mesurons des effets significatifs de l'entraînement à la CC, Nous observons un taux de participation aux séances de 96.25%

, Nous étudions le cas de M. D (70 ans) en rémission complète d'un lymphome diagnostiqué en février 2017, traité par chimiothérapie puis autogreffe en juin 2018. M. D a intégré en juillet 2018 une étude clinique comprenant un programme de Cohérence Cardiaque (CC) et d'Activité Physique Adaptée

, Les interventions se sont déroulées sur 12 semaines : 10 séances de CC (1h) avec biofeedback et autoentraînement quotidien (20 min) en plus de 2 séances d'APA (1h) par semaine. M. D a participé à 10 séances et 20 min/jour de CC

, La qualité de vie (SF36) et la Variabilité de la Fréquence Cardiaque (VFC) (enregistrements de 5min) ont été évaluées avant (T1), à la moitié (T2) et à la, p.3

, Les scores résumés physique et psychique sur 100 s'améliorent de façon cliniquement significative avec respectivement 47,0 et 42,2 à T1 ; 50,5 et 61,8 à T2 ; 55,6 et 61,2 à T3. Les mesures de VFC montrent une augmentation du SDNN (Standard Deviation of Normal to Normal R-R interval) avec 17,8ms à T1, vol.18

, L'entretien révèle une amélioration perçue des capacités physiques, du moral et une reprise des activités quotidiennes en lien avec le programme. M. D se souvient : « j'avais perdu vraiment espoir, avec la maladie » ; alors qu'aujourd'hui : « j'oublie que j'ai été malade des fois