The spatio-temporal study revealed that the household solid waste generated in Moroni and Foumbouni are of the same nature, but may vary from one region to another. However, 2019 represents the reference year since the study took place before the arrival of COVID19. The monthly salary, the number of adults, and the number of employees are positively correlated with the production of HSW. With a production of more than 50% of bio-waste and about 40% of fuel, two ways of energy recovery are the most suitable in Comoros: methanation and gasification. However, to choose the best valorization technique, other studies deserve to be carried out.