Abstract : Marine sponges are recognized as a rich source of new marine natural products. In this study, chemical investigation of the CH 2 Cl 2-MeOH (1:1) extract from the marine sponge Haliclona fascigera collected in Mayotte was carried out and highlighted a new unusual acetylenic and tetrahydrofuranic fatty acid, (2S*,5S*,6Z)-2,5-epoxydocosan-6-en-21-ynoic acid (1). Its planar structure was elucidated by HRESIMS data, IR, 1D and 2D NMR spectra. The relative configuration of compound 1 was deduced from density functional theory (DFT) computational calculations fitted using the recently published DP4+ probability.
http://hal.univ-reunion.fr/hal-01866080
Contributor : Réunion Univ
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Submitted on : Monday, September 3, 2018 - 7:52:37 AM
Last modification on : Thursday, March 28, 2019 - 11:24:13 AM
Long-term archiving on : Tuesday, December 4, 2018 - 1:57:42 PM
