Amphimedonoic acid and psammaplysene E, novel brominated alkaloids from Amphimedon sp.

Examination of the CH2Cl2-MeOH (1:1) extract from the Madagascan sponge Amphimedon sp. highlighted two new brominated alkaloids, amphimedonoic acid (1) and psammaplysene E (2), along with the known 3,5-dibromo-4-methoxybenzoic acid (3). Their structures were elucidated by 1D and 2D NMR spectroscopy and HRESIMS data.

Keywords

Bromotyrosine derivated Amphimedon Alkaloids Marine sponge

Domains

Medicinal Chemistry

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12- Campos et al, Tetrahedron letters 2017_hal.pdf (1.04 Mo)

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https://hal.univ-reunion.fr/hal-01657062

Submitted on : Wednesday, December 6, 2017-12:16:56 PM

Last modification on : Monday, November 6, 2023-12:08:23 PM

Dates and versions

hal-01657062 , version 1 (06-12-2017)

Identifiers

HAL Id : hal-01657062 , version 1
DOI : 10.1016/j.tetlet.2017.08.072

Cite

Pierre-Éric Campos, Jean-Luc Wolfender, Emerson F. Queiroz, Laurence Marcourt, Ali Al-Mourabit, et al.. Amphimedonoic acid and psammaplysene E, novel brominated alkaloids from Amphimedon sp.. Tetrahedron Letters, 2017, 58 (40), pp.3901-3904. ⟨10.1016/j.tetlet.2017.08.072⟩. ⟨hal-01657062⟩

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