Amphimedonoic acid and psammaplysene E, novel brominated alkaloids from Amphimedon sp.

Pierre-Éric Campos; Jean-Luc Wolfender; Emerson F. Queiroz; Laurence Marcourt; Ali Al-Mourabit; Nicole de Voogd; Bertrand Illien; Anne Gauvin-Bialecki

doi:10.1016/j.tetlet.2017.08.072

Journal articles

Amphimedonoic acid and psammaplysene E, novel brominated alkaloids from Amphimedon sp.

Pierre-Éric Campos ¹ Jean-Luc Wolfender ^{2, 3} Emerson F. Queiroz ^{2, 3} Laurence Marcourt ^{3, 2} Ali Al-Mourabit ⁴ Nicole de Voogd ⁵ Bertrand Illien ¹ Anne Gauvin-Bialecki ¹

1 LCSNSA - Laboratoire de Chimie des Substances Naturelles et des Sciences des Aliments

2 UNIGE - Université de Genève = University of Geneva

3 UNIL - Université de Lausanne = University of Lausanne

4 ICSN - Institut de Chimie des Substances Naturelles

5 Naturalis Biodiversity Center [Leiden]

Abstract : Examination of the CH2Cl2-MeOH (1:1) extract from the Madagascan sponge Amphimedon sp. highlighted two new brominated alkaloids, amphimedonoic acid (1) and psammaplysene E (2), along with the known 3,5-dibromo-4-methoxybenzoic acid (3). Their structures were elucidated by 1D and 2D NMR spectroscopy and HRESIMS data.

Keywords : Bromotyrosine derivated Amphimedon Alkaloids Marine sponge

Document type :

Journal articles

Domain :

Chemical Sciences / Medicinal Chemistry

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Submitted on : Wednesday, December 6, 2017 - 12:16:56 PM
Last modification on : Friday, September 30, 2022 - 11:26:51 AM

Amphimedonoic acid and psammaplysene E, novel brominated alkaloids from Amphimedon sp.

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Amphimedonoic acid and psammaplysene E, novel brominated alkaloids from Amphimedon sp.

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