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Chikungunya virus takes centre stage in virally induced arthritis: possible cellular and molecular mechanisms to pathogenesis

Marie-Christine Jaffar-Bandjee 1, 2 Trina Das 1 Jean-Jacques Hoarau 1 Pascale Krejbich-Trotot 1 Mélanie Denizot 1 Anne Ribera 1 Pierre Roques 3, 4 Philippe Gasque 1
1 GRI - Groupe de Recherche en Immunopathologies et maladies infectueuses
2 CHU La Réunion - Centre Hospitalier Universitaire de La Réunion
3 IDMIT - Infectious Diseases Models for Innovative Therapies
4 UP11 - Université Paris-Sud - Paris 11
Abstract : Chikungunya virus (CHIKV) causes an acute symptomatic illness with fever, skin rash (hypersensitivity vascultis), incapacitating arthralgia which can evolve to chronic arthritis in elderly patients. Clinical observations from cohort studies have been corroborated with data from experimental infection in several mouse and non-human primate models as discussed herein.
Keywords : Arthritis immunology Virus
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Journal articles
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https://hal.univ-reunion.fr/hal-01274636
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Submitted on : Tuesday, February 16, 2016 - 8:43:30 AM
Last modification on : Thursday, September 17, 2020 - 3:06:23 AM

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Marie-Christine Jaffar-Bandjee, Trina Das, Jean-Jacques Hoarau, Pascale Krejbich-Trotot, Mélanie Denizot, et al.. Chikungunya virus takes centre stage in virally induced arthritis: possible cellular and molecular mechanisms to pathogenesis. Microbes and Infection, Elsevier, 2009, Forum on Chikungunya, 11 (14–15), pp.1206--1218. ⟨10.1016/j.micinf.2009.10.001⟩. ⟨hal-01274636⟩

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