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A226V Strains of Chikungunya Virus, Réunion Island, 2010

Abstract : Chikungunya virus (CHIKV) first emerged in Indian Ocean islands off the eastern coast of Africa in 2005 and was responsible for large-scale epidemics on the islands of Réunion, Comoros, Mayotte, Mauritius, Madagascar, and Seychelles (1–4). On Réunion Island, a French overseas territory of 810,000 inhabitants, herd immunity reached 38% in October 2006 (5). Molecular epidemiology of the strain responsible for these outbreaks indicated that it had originated in Kenya (6). The epidemic on Réunion Island was associated with a mutation in the envelope protein gene (E1-A226V) that improves replication and transmission efficiency in Aedes albopictus mosquitoes (7).
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Eric D’ortenzio, Marc Grandadam, Elsa Balleydier, Marie-Christine Jaffar-Bandjee, Alain Michault, et al.. A226V Strains of Chikungunya Virus, Réunion Island, 2010. Emerging Infectious Diseases, Centers for Disease Control and Prevention, 2011, 17 (2), pp.309--311. ⟨10.3201/eid1702.101056⟩. ⟨hal-01274613⟩

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