J. Strauss and E. Strauss, The alphaviruses: gene expression, replication, and evolution, Microbiol Rev, vol.58, issue.3, pp.491-562, 1994.

G. Borgherini and P. Poubeau, Persistent arthralgia associated with chikungunya virus: a study of 88 adult patients on reunion island. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America, pp.469-475, 2008.

J. Staples and R. Breiman, Chikungunya Fever: An Epidemiological Review of a Re???Emerging Infectious Disease, Clinical Infectious Diseases, vol.49, issue.6, pp.942-948, 2009.
DOI : 10.1086/605496

M. Robinson, An epidemic of virus disease in Southern Province, Tanganyika territory, in 1952???1953, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol.29, issue.1, pp.28-32, 1955.
DOI : 10.1016/0035-9203(48)90352-6

T. Couderc and F. Chretien, A Mouse Model for Chikungunya: Young Age and Inefficient Type-I Interferon Signaling Are Risk Factors for Severe Disease, PLoS Pathogens, vol.41, issue.2, p.29, 2008.
DOI : 10.1371/journal.ppat.0040029.sg003

URL : https://hal.archives-ouvertes.fr/pasteur-01402310

T. Das and M. Jaffar-bandjee, Chikungunya fever: CNS infection and pathologies of a re-emerging arbovirus, Progress in Neurobiology, vol.91, issue.2, pp.121-129, 2010.
DOI : 10.1016/j.pneurobio.2009.12.006

URL : https://hal.archives-ouvertes.fr/hal-01274626

Z. Her and B. Malleret, Active Infection of Human Blood Monocytes by Chikungunya Virus Triggers an Innate Immune Response, The Journal of Immunology, vol.184, issue.10, pp.5903-5913, 2010.
DOI : 10.4049/jimmunol.0904181

P. Krejbich-trotot and M. Denizot, Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses, The FASEB Journal, vol.73, issue.1, pp.314-325, 2010.
DOI : 10.4049/jimmunol.0900255

URL : https://hal.archives-ouvertes.fr/hal-01274616

C. Schilte and T. Couderc, Type I IFN controls chikungunya virus via its action on nonhematopoietic cells, The Journal of Experimental Medicine, vol.58, issue.2, pp.429-442, 2010.
DOI : 10.1038/77553

URL : https://hal.archives-ouvertes.fr/pasteur-00458108

M. Sourisseau and C. Schilte, Characterization of Reemerging Chikungunya Virus, PLoS Pathogens, vol.4, issue.6, p.89, 2007.
DOI : 0889-2229(1988)004[0441:ARASTF]2.0.CO;2

URL : https://hal.archives-ouvertes.fr/pasteur-00161827

A. Khan and K. Morita, Complete nucleotide sequence of chikungunya virus and evidence for an internal polyadenylation site, Journal of General Virology, vol.28, issue.12, pp.3075-3084, 2002.
DOI : 10.1016/0042-6822(84)90428-8

E. Strauss and J. Strauss, Structure and Replication of the Alphavirus Genome, 1986.
DOI : 10.1007/978-1-4757-0785-4_3

S. Faragher and A. Meek, Genome sequences of a mouse-avirulent and a mouse-virulent strain of ross river virus, Virology, vol.163, issue.2, pp.509-526, 1988.
DOI : 10.1016/0042-6822(88)90292-9

J. Strauss and E. Strauss, Evolution of RNA Viruses, Annual Review of Microbiology, vol.42, issue.1, pp.657-683, 1988.
DOI : 10.1146/annurev.mi.42.100188.003301

T. Ito and R. Amakawa, Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets, J Exp Med, issue.11, pp.1951507-1512, 2002.

A. Iwasaki and R. Medzhitov, Toll-like receptor control of the adaptive immune responses, Nature Immunology, vol.298, issue.10, pp.987-995, 2004.
DOI : 10.1126/science.1076071

H. Kato and S. Sato, Cell Type-Specific Involvement of RIG-I in Antiviral Response, Immunity, vol.23, issue.1, pp.19-28, 2005.
DOI : 10.1016/j.immuni.2005.04.010

T. Kawai and K. Takahashi, IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction, Nature Immunology, vol.174, issue.10, pp.981-988, 2005.
DOI : 10.4049/jimmunol.174.4.2273

S. Diebold and T. Kaisho, Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA, Science, vol.303, issue.5663, pp.1529-1531, 2004.
DOI : 10.1126/science.1093616

F. Heil and H. Hemmi, Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8, Science, vol.303, issue.5663, pp.1526-1529, 2004.
DOI : 10.1126/science.1093620

J. Lund and L. Alexopoulou, Recognition of single-stranded RNA viruses by Toll-like receptor 7, Proceedings of the National Academy of Sciences, vol.48, issue.3, pp.5598-5603, 2004.
DOI : 10.1002/cyto.10118

URL : http://www.pnas.org/content/101/15/5598.full.pdf

J. Rehwinkel, R. Sousa, and C. , RIGorous Detection: Exposing Virus Through RNA Sensing, Science, vol.138, issue.3, pp.284-286
DOI : 10.1016/j.cell.2009.06.015

M. Mori and M. Yoneyama, Identification of Ser-386 of Interferon Regulatory Factor 3 as Critical Target for Inducible Phosphorylation That Determines Activation, Journal of Biological Chemistry, vol.169, issue.11, pp.2799698-9702, 2004.
DOI : 10.1038/nsb1001

URL : http://www.jbc.org/content/279/11/9698.full.pdf

M. Yoneyama and W. Suhara, Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300, The EMBO Journal, vol.17, issue.4, pp.1087-1095, 1998.
DOI : 10.1093/emboj/17.4.1087

M. Yoneyama and W. Suhara, Review: Control of IRF-3 Activation by Phosphorylation, Journal of Interferon & Cytokine Research, vol.22, issue.1, pp.73-76, 2002.
DOI : 10.1089/107999002753452674

L. Malmgaard, Induction and Regulation of IFNs During Viral Infections, Journal of Interferon & Cytokine Research, vol.24, issue.8, pp.439-454, 2004.
DOI : 10.1089/1079990041689665

T. Taniguchi and A. Takaoka, The interferon-??/?? system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors, Current Opinion in Immunology, vol.14, issue.1, pp.111-116, 2002.
DOI : 10.1016/S0952-7915(01)00305-3

R. Randall and S. Goodbourn, Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures, Journal of General Virology, vol.356, issue.1
DOI : 10.1016/j.bbrc.2007.02.101

URL : http://jgv.microbiologyresearch.org/deliver/fulltext/jgv/89/1/1.pdf?itemId=/content/journal/jgv/10.1099/vir.0.83391-0&mimeType=pdf&isFastTrackArticle=

, J Gen Virol, vol.89, pp.1-47, 2008.

M. Clemens, PKR???A protein kinase regulated by double-stranded RNA, The International Journal of Biochemistry & Cell Biology, vol.29, issue.7, pp.945-949, 1997.
DOI : 10.1016/S1357-2725(96)00169-0

C. Samuel, Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities, Virology, vol.183, issue.1, pp.1-11, 1991.
DOI : 10.1016/0042-6822(91)90112-O

L. White and T. Sali, Chikungunya Virus Induces IPS-1-Dependent Innate Immune Activation and Protein Kinase R-Independent Translational Shutoff, Journal of Virology, vol.85, issue.1, pp.606-620, 2011.
DOI : 10.1128/JVI.00767-10

J. Hoarau, J. Bandjee, and M. , Persistent Chronic Inflammation and Infection by Chikungunya Arthritogenic Alphavirus in Spite of a Robust Host Immune Response, The Journal of Immunology, vol.184, issue.10, pp.5914-5927, 2010.
DOI : 10.4049/jimmunol.0900255

URL : https://hal.archives-ouvertes.fr/hal-01285461

J. Fros and W. Liu, Chikungunya Virus Nonstructural Protein 2 Inhibits Type I/II Interferon-Stimulated JAK-STAT Signaling, Journal of Virology, vol.84, issue.20, pp.10877-10887, 2010.
DOI : 10.1128/JVI.00949-10

L. Breakwell and P. Dosenovic, Semliki Forest Virus Nonstructural Protein 2 Is Involved in Suppression of the Type I Interferon Response, Journal of Virology, vol.81, issue.16, pp.818677-8684, 2007.
DOI : 10.1128/JVI.02411-06