Isohalitulin and Haliclorensins B and C, Three Marine Alkaloids from Haliclona tulearensis

Abstract : Three new alkaloids, designated isohalitulin (I), haliclorensin B (II), and haliclorensin C (III), were isolated from 2 specimens of the Madagascan sponge Haliclona tulearensis, collected at 2 locations in Salary Bay, north of Tulear. Their structures were elucidated by extensive spectroscopic means. I-III exhibited mild toxicity in the brine shrimp test. [on SciFinder(R)]