Socioeconomic and environmental determinants of dengue transmission in an urban setting: An ecological study in Nouméa, New Caledonia

Abstract : Background: Dengue is a mosquito-borne virus that causes extensive morbidity and economic loss in many tropical and subtropical regions of the world. Often present in cities, dengue virus is rapidly spreading due to urbanization, climate change and increased human movements. Dengue cases are often heterogeneously distributed throughout cities, suggesting that small-scale determinants influence dengue urban transmission. A better understanding of these determinants is crucial to efficiently target prevention measures such as vector control and education. The aim of this study was to determine which socioeconomic and environmental determinants were associated with dengue incidence in an urban setting in the Pacific. Methodology: An ecological study was performed using data summarized by neighborhood (i.e. the neighborhood is the unit of analysis) from the last two dengue epidemics (2008–2009 and 2012–2013) in the city of Nouméa, the capital of New Caledonia. Spatial patterns and hotspots of dengue transmission were assessed using global and local Moran’s I statistics. Multivariable negative binomial regression models were used to investigate the association between dengue incidence and various socioeconomic and environmental factors throughout the city. Principal findings: The 2008–2009 epidemic was spatially structured, with clusters of high and low incidence neighborhoods. In 2012–2013, dengue incidence rates were more homogeneous throughout the city. In all models tested, higher dengue incidence rates were consistently associated with lower socioeconomic status (higher unemployment, lower revenue or higher percentage of population born in the Pacific, which are interrelated). A higher percentage of apartments was associated with lower dengue incidence rates during both epidemics in all models but one. A link between vegetation coverage and dengue incidence rates was also detected, but the link varied depending on the model used. Conclusions: This study demonstrates a robust spatial association between dengue incidence rates and socioeconomic status across the different neighborhoods of the city of Nouméa. Our findings provide useful information to guide policy and help target dengue prevention efforts where they are needed most.
Type de document :
Article dans une revue
PLoS Neglected Tropical Diseases, Public Library of Science, 2017, 11 (4), pp. e0005471. 〈http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005471〉. 〈10.1371/journal.pntd.0005471〉
Liste complète des métadonnées

Littérature citée [63 références]  Voir  Masquer  Télécharger

http://hal.univ-reunion.fr/hal-01502926
Contributeur : Réunion Univ <>
Soumis le : jeudi 7 juin 2018 - 15:23:49
Dernière modification le : mercredi 18 juillet 2018 - 20:02:03

Fichier

journal.pntd.0005471.pdf
Fichiers éditeurs autorisés sur une archive ouverte

Identifiants

Citation

Raphaël M. Zellweger, Jorge Cano, Morgan Mangeas, François Taglioni, Alizé Mercier, et al.. Socioeconomic and environmental determinants of dengue transmission in an urban setting: An ecological study in Nouméa, New Caledonia. PLoS Neglected Tropical Diseases, Public Library of Science, 2017, 11 (4), pp. e0005471. 〈http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005471〉. 〈10.1371/journal.pntd.0005471〉. 〈hal-01502926〉

Partager

Métriques

Consultations de la notice

1841

Téléchargements de fichiers

30