M. Song, K. Kim, J. Yoon, and J. Kim, Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes, Biochemical and Biophysical Research Communications, vol.346, issue.3, pp.739-745, 2006.
DOI : 10.1016/j.bbrc.2006.05.170

J. Senn, P. Klover, I. Nowak, and R. Mooney, Interleukin-6 Induces Cellular Insulin Resistance in Hepatocytes, Diabetes, vol.51, issue.12, pp.3391-3399, 2002.
DOI : 10.2337/diabetes.51.12.3391

URL : http://diabetes.diabetesjournals.org/content/diabetes/51/12/3391.full.pdf

P. Kern, S. Ranganathan, C. Li, L. Wood, and G. Ranganathan, Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance, American Journal of Physiology-Endocrinology and Metabolism, vol.84, issue.5, pp.745-751, 2001.
DOI : 10.1046/j.1464-5491.1999.00052.x

S. Creely, P. Mcternan, C. Kusminski, M. Fisher, D. Silva et al., Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes, American Journal of Physiology-Endocrinology and Metabolism, vol.292, issue.3, pp.740-747, 2007.
DOI : 10.1074/jbc.M209033200

URL : http://ajpendo.physiology.org/content/ajpendo/292/3/E740.full.pdf

J. Bastard, M. Maachi, V. Nhieu, J. Jardel, C. Bruckert et al., The Journal of Clinical Endocrinology & Metabolism, vol.87, issue.5, pp.2084-2089, 2002.
DOI : 10.1210/jcem.87.5.8450

S. Weisberg, D. Mccann, M. Desai, M. Rosenbaum, R. Leibel et al., Obesity is associated with macrophage accumulation in adipose tissue, Journal of Clinical Investigation, vol.112, issue.12, pp.1796-1808, 2003.
DOI : 10.1172/JCI19246DS1

K. Coenen, M. Gruen, A. Chait, and A. Hasty, Diet-Induced Increases in Adiposity, but Not Plasma Lipids, Promote Macrophage Infiltration Into White Adipose Tissue, Diabetes, vol.56, issue.3, pp.564-573, 2007.
DOI : 10.2337/db06-1375

S. Bes-houtmann, R. Roche, L. Hoareau, M. Gonthier, F. Festy et al., Presence of functional TLR2 and TLR4 on human adipocytes, Histochemistry and Cell Biology, vol.59, issue.Supp l1, pp.131-137, 2007.
DOI : 10.4049/jimmunol.166.1.249

URL : https://hal.archives-ouvertes.fr/hal-02301479

L. Hoareau, P. Ravanan, M. Gonthier, P. Delarue, J. Goncalves et al., Effect of PEA on LPS inflammatory action in human adipocytes, Cytokine, vol.34, issue.5-6, pp.291-296, 2006.
DOI : 10.1016/j.cyto.2006.06.005

J. Campbell, C. Ciesielski, A. Hunt, N. Horwood, J. Beech et al., A Novel Mechanism for TNF-?? Regulation by p38 MAPK: Involvement of NF-??B with Implications for Therapy in Rheumatoid Arthritis, The Journal of Immunology, vol.173, issue.11, pp.6928-6937, 2004.
DOI : 10.4049/jimmunol.173.11.6928

T. Bruggen-van-der, S. Nijenhuis, E. Van-raaij, J. Verhoef, and B. Van-asbeck, Lipopolysaccharide-induced tumor necrosis factor alpha production by human monocytes involves the raf-1/MEK1-MEK2/ERK1-ERK2 pathway, Infect Immun, vol.67, pp.3824-3829, 1999.

S. Tudhope, T. Finney-hayward, A. Nicholson, R. Mayer, M. Barnette et al., Different Mitogen-Activated Protein Kinase-Dependent Cytokine Responses in Cells of the Monocyte Lineage, Journal of Pharmacology and Experimental Therapeutics, vol.324, issue.1, pp.306-312, 2008.
DOI : 10.1124/jpet.107.127670

K. Rutault, C. Hazzalin, and L. Mahadevan, Combinations of ERK and p38 MAPK Inhibitors Ablate Tumor Necrosis Factor-?? (TNF-??) mRNA Induction, Journal of Biological Chemistry, vol.95, issue.9, pp.6666-6674, 2001.
DOI : 10.1016/S0014-5793(00)02084-6

G. Lagoumintzis, P. Xaplanteri, G. Dimitracopoulos, and F. Paliogianni, Lipopolysaccharide or Slime-glycolipoprotein in Human Monocytes is Regulated at the Level of Mitogen-activated Protein Kinase Activity: A Distinct Role of Toll-like Receptor 2 and 4, Scandinavian Journal of Immunology, vol.277, issue.2, pp.193-203, 2008.
DOI : 10.4049/jimmunol.173.3.2031

S. Yoon, S. Goh, J. Chun, E. Cho, M. Lee et al., ??-Melanocyte-stimulating Hormone Inhibits Lipopolysaccharide-induced Tumor Necrosis Factor-?? Production in Leukocytes by Modulating Protein Kinase A, p38 Kinase, and Nuclear Factor ??B Signaling Pathways, Journal of Biological Chemistry, vol.55, issue.35, pp.32914-32920, 2003.
DOI : 10.1073/pnas.080583397

S. Gangloff, U. Zahringer, C. Blondin, M. Guenounou, J. Silver et al., Influence of CD14 on Ligand Interactions between Lipopolysaccharide and Its Receptor Complex, The Journal of Immunology, vol.175, issue.6, pp.3940-3945, 2005.
DOI : 10.4049/jimmunol.175.6.3940

F. Festy, L. Hoareau, S. Bes-houtmann, A. Pequin, M. Gonthier et al., Surface protein expression between human adipose tissue-derived stromal cells and mature adipocytes, Histochemistry and Cell Biology, vol.339, issue.2, pp.113-121, 2005.
DOI : 10.1016/S0006-2952(03)00154-0

L. Hoareau, M. Buyse, F. Festy, P. Ravanan, M. Gonthier et al., Anti-inflammatory Effect of Palmitoylethanolamide on Human Adipocytes, Obesity, vol.406, issue.3, pp.431-438, 2009.
DOI : 10.1016/S0014-2999(00)00653-1

URL : https://hal.archives-ouvertes.fr/hal-01198351

O. Vitseva, K. Tanriverdi, T. Tchkonia, J. Kirkland, M. Mcdonnell et al., Inducible Toll-like Receptor and NF-??B Regulatory Pathway Expression in Human Adipose Tissue, Obesity, vol.292, issue.5, pp.932-937, 2008.
DOI : 10.1152/ajpregu.00397.2004

T. Suganami, K. Tanimoto-koyama, J. Nishida, M. Itoh, X. Yuan et al., Role of the Toll-like Receptor 4/NF-??B Pathway in Saturated Fatty Acid-Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.27, issue.1, pp.84-91, 2007.
DOI : 10.1161/01.ATV.0000251608.09329.9a

J. Laurencikiene, V. Van-harmelen, A. Nordstrom, E. Dicker, A. Blomqvist et al., NF-??B is important for TNF-??-induced lipolysis in human adipocytes, Journal of Lipid Research, vol.389, issue.5, pp.1069-1077, 2007.
DOI : 10.1007/s00125-006-0272-x

URL : http://www.jlr.org/content/48/5/1069.full.pdf

K. Ajuwon and M. Spurlock, Adiponectin inhibits LPS-induced NF-??B activation and IL-6 production and increases PPAR??2 expression in adipocytes, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, vol.288, issue.5, pp.1220-1225, 2005.
DOI : 10.1038/sj.ijo.0802496

URL : http://ajpregu.physiology.org/content/ajpregu/288/5/R1220.full.pdf

M. Moro, O. Hurtado, A. Cardenas, C. Romera, J. Madrigal et al., Expression and Function of Tumour Necrosis Factor-??-Converting Enzyme in the Central Nervous System, Neurosignals, vol.12, issue.2, pp.53-58, 2003.
DOI : 10.1159/000071814

M. Kawaguchi, Y. Mitsuhashi, and S. Kondo, Localization of tumour necrosis factor-alpha converting enzyme in normal human skin, Clinical and Experimental Dermatology, vol.155, issue.2, pp.185-187, 2004.
DOI : 10.1007/s004030050317

L. Armstrong, S. Godinho, K. Uppington, H. Whittington, and A. Millar, Contribution of TNF-?? Converting Enzyme and Proteinase-3 to TNF-?? Processing in Human Alveolar Macrophages, American Journal of Respiratory Cell and Molecular Biology, vol.34, issue.2, pp.219-225, 2006.
DOI : 10.1042/0264-6021:3570787

URL : http://intl-ajrcmb.atsjournals.org/content/34/2/219.full.pdf

S. Su, K. Hua, H. Lee, L. Chao, S. Tan et al., LTA and LPS mediated activation of protein kinases in the regulation of Hoareau et al, Journal of Inflammation, vol.7, issue.1, 2010.

, inflammatory cytokines expression in macrophages, Clin Chim Acta, vol.374, pp.106-115, 2006.

M. Guha and N. Mackman, The Phosphatidylinositol 3-Kinase-Akt Pathway Limits Lipopolysaccharide Activation of Signaling Pathways and Expression of Inflammatory Mediators in Human Monocytic Cells, Journal of Biological Chemistry, vol.69, issue.35, pp.32124-32132, 2002.
DOI : 10.1016/S1097-2765(01)00361-6

M. Hoch, A. Eberle, R. Peterli, T. Peters, D. Seboek et al., LPS induces interleukin-6 and interleukin-8 but not tumor necrosis factor-?? in human adipocytes, Cytokine, vol.41, issue.1, pp.29-37, 2008.
DOI : 10.1016/j.cyto.2007.10.008

T. Okada, Y. Kawano, T. Sakakibara, O. Hazeki, and M. Ui, Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin, J Biol Chem, vol.269, pp.3568-3573, 1994.

S. Sorensen, D. Linseman, E. Mcewen, A. Heacock, and S. Fisher, A role for a wortmannin-sensitive phosphatidylinositol-4-kinase in the endocytosis of muscarinic cholinergic receptors, Mol Pharmacol, vol.53, pp.827-836, 1998.

C. Vlahos, W. Matter, K. Hui, and R. Brown, A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002), J Biol Chem, vol.269, pp.5241-5248, 1994.

L. Kidd, G. Schabbauer, J. Luyendyk, T. Holscher, R. Tilley et al., Insulin Activation of the Phosphatidylinositol 3-Kinase/Protein Kinase B (Akt) Pathway Reduces Lipopolysaccharide-Induced Inflammation in Mice, Journal of Pharmacology and Experimental Therapeutics, vol.326, issue.1, pp.348-353, 2008.
DOI : 10.1124/jpet.108.138891

M. Poggi, D. Bastelica, P. Gual, M. Iglesias, T. Gremeaux et al., C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet, Diabetologia, vol.11, issue.6, pp.1267-1276, 2007.
DOI : 10.1152/ajpendo.00332.2001

P. Cani, J. Amar, M. Iglesias, M. Poggi, C. Knauf et al., Metabolic Endotoxemia Initiates Obesity and Insulin Resistance, Diabetes, vol.56, issue.7, pp.1761-1772, 2007.
DOI : 10.2337/db06-1491

D. Tsukumo, M. Carvalho-filho, J. Carvalheira, P. Prada, S. Hirabara et al., Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance, Diabetes, vol.56, issue.8, pp.1986-1998, 2007.
DOI : 10.2337/db06-1595

H. Shi, M. Kokoeva, K. Inouye, I. Tzameli, H. Yin et al., TLR4 links innate immunity and fatty acid???induced insulin resistance, Journal of Clinical Investigation, vol.116, issue.11, pp.3015-3025, 2006.
DOI : 10.1172/JCI28898

F. Kim, M. Pham, I. Luttrell, D. Bannerman, J. Tupper et al., Toll-Like Receptor-4 Mediates Vascular Inflammation and Insulin Resistance in Diet-Induced Obesity, Circulation Research, vol.100, issue.11, pp.1589-1596, 2007.
DOI : 10.1161/CIRCRESAHA.106.142851

K. Pou, J. Massaro, U. Hoffmann, R. Vasan, P. Maurovich-horvat et al., Visceral and Subcutaneous Adipose Tissue Volumes Are Cross-Sectionally Related to Markers of Inflammation and Oxidative Stress: The Framingham Heart Study, Circulation, vol.116, issue.11, pp.1234-1241, 2007.
DOI : 10.1161/CIRCULATIONAHA.107.710509

B. Galvez, S. Martin, N. Rodriguez, and C. , TNF-alpha Is Required for the Attraction of Mesenchymal Precursors to White Adipose Tissue in Ob/ob Mice, PLoS ONE, vol.30, issue.2, p.4444, 2009.
DOI : 10.1371/journal.pone.0004444.s006

. Hoareau, Cite this article as Signaling pathways involved in LPS induced TNFalpha production in human adipocytes, Journal of Inflammation, 2001.
DOI : 10.1186/1476-9255-7-1

URL : https://journal-inflammation.biomedcentral.com/track/pdf/10.1186/1476-9255-7-1?site=journal-inflammation.biomedcentral.com