Taumycins A and B, Two Bioactive Lipodepsipeptides from the Madagascar Sponge Fascaplysinopsis sp

Abstract : Two closely related lipodepsipeptides, taumycins A and B (I and II) have been isolated from the Madagascar sponge Fascaplysinopsis sp. The two compds. have the same 12-membered oxodepsipeptide ring system in common. Both were toxic to brine shrimp larvae, and taumycin A (1 μM), but not taumycin B, inhibited growth of the human UT-7 leukemic cell line. The structure of the two compds., likely to be derived from microorganisms, was established by MS and 1D and 2D NMR data. [on SciFinder(R)]
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Organic Letters, American Chemical Society, 2008, 10 (19), pp.4307--4309. 〈10.1021/ol801750y〉
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http://hal.univ-reunion.fr/hal-01188151
Contributeur : Claire Tessier <>
Soumis le : vendredi 28 août 2015 - 15:08:24
Dernière modification le : vendredi 14 septembre 2018 - 08:17:11

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Ashgan Bishara, Amira Rudi, Maurice Aknin, Drorit Neumann, Nathalie Ben-Califa, et al.. Taumycins A and B, Two Bioactive Lipodepsipeptides from the Madagascar Sponge Fascaplysinopsis sp. Organic Letters, American Chemical Society, 2008, 10 (19), pp.4307--4309. 〈10.1021/ol801750y〉. 〈hal-01188151〉

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