Saldedines A and B, Dibromo Proaporphine Alkaloids from a Madagascan Tunicate

Abstract : Two new dibromo proaporphine alkaloids, designated saldedines A (I) and B (II), were isolated from an unidentified tunicate collected at Salary Bay, Madagascar. Saldedines A and B are the 1st marine proaporphine alkaloids. Their structures were elucidated by extensive spectroscopic means, and the structure of I was confirmed by single-crystal X-ray diffraction anal. Both saldedines A and B were tested for toxicity to brine shrimp and showed moderate activity. [on SciFinder(R)]
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Submitted on : Friday, August 28, 2015 - 3:08:07 PM
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Hagit Sorek, Amira Rudi, Israel Goldberg, Maurice Aknin, Yoel Kashman. Saldedines A and B, Dibromo Proaporphine Alkaloids from a Madagascan Tunicate. Journal of Natural Products, American Chemical Society, 2009, 72 (4), pp.784--786. 〈10.1021/np800714k〉. 〈hal-01188146〉

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