Comparison of effects from gamma, e-beam and X-ray radiation on multilayer polymer films used in biopharmaceutical devices by chemometric treatment of spectroscopic data
Résumé
The present study investigated the effects of gamma-ray, electron beam, and X-ray radiation on polymers in EVA/ EVOH/EVA multilayer films. Spectroscopic methods, including FTIR and UV-Vis, were employed in conjunction with chemometric treatments such as PCA, SIMPLISMA treatments, and PLS models. The feasibility of dose prediction on multilayer film, given a known dose, is attainable across various irradiation technologies. Both gamma ray and X-ray exhibit comparable effects on the multilayer film, and it is feasible to anticipate the dose released on the film by utilizing UV-Vis spectra or infrared spectra for gamma ray or X-ray of a predetermined dose.
Domaines
Sciences de l'ingénieur [physics]| Origine | Publication financée par une institution |
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